Dr. Bill Cortner is a successful scientist with a beautiful fiancée named Jan Compton. After a horrible car accident decapitates Jan, Dr. Cortner collects her severed head and rushes it to his laboratory, where he revives it and manages to keep it alive in a liquid-filled tray.
Dr. Cortner now decides to commit murder in order to obtain an attractive new body to attach to his fiancée's head. As he hunts for a suitable specimen, Jan begins to hatch some murder plans of her own. Filled with hatred for Cortner because he won't let her die, she communicates telepathically with a hideous mutant in the laboratory cell, telling it to kill the scientist.
The monster in the closet is played by Eddie Carmel in his first "cinematic role". Carmel was a well-known Palestine-born circus attraction who worked under the name "The Jewish Giant". He is the subject of a photograph by Diane Arbus entitled "The Jewish Giant at Home with His Parents in the Bronx, NY, 1970".
The Brain that Woudn't Die was the first movie watched by Mike Nelson in Mystery Science Theater 3000 (episode 513). The film was also featured in the Steve Martin comedy The Man with Two Brains, along with Donovan's Brain.
In 2006, the movie was adapted into a live stage production by Last Rites Productions, a Portland, Oregon theatre company. The company had previously adapted "Manos" The Hands of Fate, a subject of another Mystery Science Theater 3000 episode.
In the video game No One Lives Forever 2: A Spy In H.A.R.M.'s Way, two guards turned into "man crates" are having a conversation. One of them quotes the movie most famous line ("Like all quantities horror has it's ultimate and I am that!") and the other recognizes it and add "I've never though I would ever relate to Jan In The Pan".
Movie bio by WikiPedia
Vaselina: I bought this movie at the 99 Cent store, I saw it quite a long time ago when Elvira hosted it. I was amazed by the acting. I am not a fan of bad acting in the Horror Genre which can exclude most movies from my list of favorites.
I love the tale of love vs. morals that was made so popular from The Bride of Frankenstein. Typical, though that it should end in destruction.
To me it reminded me of a mix of both Frankenstein and The Bride of Frankenstein, keep the woman alive and to be destroyed by your own creation. Terriffic!
Even though the plot could link to other films, it was still a great original film and I loved it.